Lead Optimization
Optimize efficacy, safety, and developability with integrated multimodal workflows.
Key Capabilities
Biochemistry: Mechanistic and kinetic profiling across concentration ranges
Cell Biology: Efficacy and toxicity readouts in complex models (3D, co-culture)
Biophysics: Fine-tuned affinity and residence time analysis
Structural Biology: Iterative ligand co-crystal structures to guide selectivity and potency
Biologics: Engineering and screening of antibodies, bispecifics, and other modalities
Data Science: Custom dashboards tracking potency, exposure, and ADMET data trends
Value to Your Program
Rational, data-driven optimization supported by structural and kinetic insights
Seamless connection between chemical series and cellular phenotypes
Improved confidence in compound prioritization using integrative data
Support for both small molecules and biologics under one roof
Validation Metrics
Reduced lead optimization timelines by up to 30% across multiple programs
High-content assays enabled differentiation of lead series at cellular resolution
Supported >12 biologic candidates advancing toward IND with optimized profiles