2. Hit Identification
Rapidly identify high-quality chemical matter with robust, automated screening workflows.
Capabilities Overview
At Arctoris, we elevate biochemistry to new heights by integrating cutting-edge lab automation technology with unparalleled expertise. Our Ulysses® platform delivers high-throughput, high-precision biochemical assays, enabling rapid identification and validation of high-quality hits for even the most challenging drug targets. With tailored biochemical solutions and bespoke AI/ML-ready datasets, we transform your drug discovery process, providing exceptional data quality that drives better decisions and accelerates the development of better drugs.
Key Capabilities
Biochemistry: Fully automated enzymatic and binding assays tailored to your target
Biophysics: High-throughput kinetic and thermodynamic screening (SPR, DSF, TSA)
Cell Biology: Phenotypic screening and in-cell target engagement studies
Protein Science: Production of assay-grade proteins for screening
Data Science: Real-time hit calling, curve fitting, and statistical QC (Z’, SSMD)
Key Capabilities
High-quality, AI-ready data from day one
Ability to screen >2,000 compounds/day with automated analytics
Hit confirmation via orthogonal assay formats for increased confidence
Integration of molecular and cellular readouts for more predictive hit profiles
Validation Metrics
Z’ > 0.75 across high-throughput screens
Profiling of >2,000 compounds against 12+ targets in a single day
Curve fitting pipelines delivering IC₅₀/EC₅₀ values with <10% CV
Machine learning partners increased hit rate accuracy by >25%